In a comprehensive examination of 540 pLGG, 180 canonical KIAA1549-BRAF fusions were identified, with a prevalence of 83% in PA, as well as ganglioglioma (4.4%), diffuse astrocytoma (2.8%), glioneuronal tumors (2.2%), and desmoplastic infantile astrocytoma (0.6%), and 6.7% in pLGG NOS (44). Here, BRAF is linked to ganglioglioma.