PDCD1 and pneumonitis: Among all the ICIs, anti-PD-1 antibodies combinations and anti-CTLA-4 antibodies combinations demonstrated an association with pneumonitis [PD-1+chemotherapy: 1.76, 95% CI 1.52-2.05; CTLA-4+chemotherapy: 2.36, 95% CI 1.67-3.35], while interestingly anti-PD-L1 antibodies plus chemotherapy combinations did not show the association.