It was found that the GABPB1, is highly expressed and related to unfavorable prognosis in HCC, and could be blocked by lncRNA GABPB1-AS1, which inhibits the expression of PRDX5 (peroxiredoxin 5) peroxidase and further attenuates the antioxidant capacity of HCC cells, thus leading to an enhancement of erastin-induced ferroptosis (Qi et al., 2019). This evidence concerns the gene PRDX5 and hepatocellular carcinoma.