It is showed that PRDX1 (peroxiredoxin 1), a ferroptosis promoter, combines with GPX2, MT3 (membrane receptor 3) and SRXN1 (sulfiredoxin 1) to establish an effective prognosis model for HCC (Luo et al., 2022). The gene discussed is SRXN1; the disease is hepatocellular carcinoma.