PDHB and hepatocellular carcinoma: In the TCGA, compared to normal tissues, 17 genes were differentially expressed in HCC, including ATP7A, DLD, DLAT, DLST, SLC31A1, FDX1, LIPT1, LIAS, LIPT2, PDHA1, NFE2L2, NLRP3, GLS, MTF1, CDKN2A, DBT, and PDHB (Figure 1(a)).