NASH- Nonalcoholic steatohepatitis, CRP- C-reactive protein, PPAR- Peroxisome proliferator-activate receptor, NAS- NAFLD Activity Score, LDL-C- Low-density lipoprotein- cholesterol, EBP- Enhancer binding protein, NF-B- Nuclear factor kappa beta, IL- Interleukin, STAMTM murine model- male mouse model, QD- quaque die (daily administration). The gene discussed is PPARA; the disease is metabolic dysfunction-associated steatotic liver disease.