For BBS1, the association we found is also quite interesting in light of very recent evidence pointing to this gene, and potentially more in general the BBSome, in being involved in immune synapse assembly by promoting the centrosome polarization to the antigen-presenting cells and in the regulation of selective functions of T cells that predispone BBS patients to other autoimmune and inflammatory diseases (Kanie and Jackson, 2021; Tsyklauri et al., 2021; Stump et al., 2023). The gene discussed is BBS1; the disease is Bardet-Biedl syndrome.