GJA1 and ischemic stroke: The expression of substance P (SP), connexin 43 (Cx43), C-kit in the stomach and the intestine was decreased along with a reduced number of interstitial Cajal cells, suspension of citrus aurantium plus nimodipine significantly reversed these changes, indicating that citrus aurantium is able to protect the mucosa of the digestive tract and restore its functions after ischemic stroke (Qiu, 2014).