MBNL1 and myotonic dystrophy type 1: The study simulated the DM1-associated misbalance between two RNA binding factors, Muscleblind like splicing regulator (MBNL1) and CUGBP Elav-like family member 1 (CELF1), in the fly heart; this led to dysregulated calcium signaling genes including straightjacket (stj)/α2δ3, which encodes a voltage-gated calcium channel subunit (Auxerre-Plantié et al., 2019).