High-sugar diet diabetes model marked by hyperglycemia, hypertrehalosemia, peripheral resistance to exogenous insulin, and accumulation of triglyceride; Shortened lifespan; Structural defects include increased Pericardin deposition; Cardiac functional defects, include increased diastole and systole (without fractional shortening), and arrhythmia; Maternal inheritance. The gene discussed is INS; the disease is Arrhythmia.