NPPA and cardiac hypertrophy: Furthermore, through Pearson correlation analysis in R, we discovered a significant positive correlation between SSC5D and the cardiac hypertrophy marker genes A-type natriuretic peptide (NPPA) (R = 0.6, p = 3.1e-11) and B-type natriuretic peptide (NPPB) (R = 0.46, p = 1.3e-6) (Figures 1C, D).