While in patients with NAFLD subtype C, the relationship between VLDL-TG and VLDL-Apo-B levels and the degree of steatosis was curvilinear, reaching a plateau at steatosis grade S2 (34–66% of hepatocytes contained fat), in patients with subtype A, the levels of VLDL-TG and VLDL-Apo-B were independent of the grade of steatosis from S1 (5–33% of hepatocytes contained fat) to S3 (more than 66% of hepatocytes contained fat) [83]. The gene discussed is APOB; the disease is metabolic dysfunction-associated steatotic liver disease.