APOE and type 2 diabetes mellitus: Moreover, in patients with T2DM, participants in the E4 (ɛ3/ɛ4, ɛ4/ɛ4) group had significantly higher lipid profiles than those in the E3 (ɛ3/ɛ3) group, while participants in the E2 group (ɛ2/ɛ2, ɛ2/ɛ3) showed lower TC, LDL-C, and ApoE-A1 levels than those in the E3 (ɛ3/ɛ3) group.