IL17A and Cowden disease: Analysis revealed that the main IL-17 producer in colonic inflammatory tissues is NCR-ILC3, and the increased amount of NCR-ILC3 in CD patients is also accompanied by a reduced frequency of further investigation of innate immune cells isolated from the inflamed colon in the lamina propria of IBD patients revealed elevated expression of ILC3-related genes, with IL-17 exhibiting the highest expression (100).