IFN-γ is important for limiting the growth of tachyzoites in the early stages of infection, inhibiting the reactivation of dormant T. gondii cysts (51), inhibiting the growth and reproduction of T. gondii through the degradation of amino acids (tryptophan, L-arginine) essential for growth, and by inducing immune-related GTPases (IRGs), which can destroy vacuoles and eliminate parasites by lysosome-mediated degradation (48, 52). This evidence concerns the gene IFNG and infection.