CD79A and B-cell chronic lymphocytic leukemia: Hypogammaglobulinemia (HGG) is defined as a reduced concentration of immunoglobulin G (IgG) and/or immunoglobulin A (IgA) in the serum (while immunoglobulin M levels may vary) and is a well-known condition present in hematological malignancies, commonly observed in chronic lymphocytic leukemia (CLL) (1).