IL6 and laryngotracheoesophageal cleft: In a prior study, our group conducted a meta-analysis examining the relationship between mutations in the IL-6 and IL-10 genes (rs1800871, rs1800872, rs1800795, rs1800796, rs1800797, rs1800896) and LC risk, ultimately identifying the IL-10 -592 and -1082 polymorphisms as being closely linked to LC susceptibility(14).