CD63 and central nervous system cancer: In addition, biotinylated antibody-functionalized titanium nitride (BAF-TiN) and titanium dioxide (TiO2)-related LSPR can quantitatively detect exosomes isolated from human glioma cells, recognizing the exosomal marker membrane protein CD63, and BAF-TiN can also recognize glioma-specific variants of epidermal growth factor receptor variant-III (68).