Stroke was significantly associated with aPC IgG (OR 2.272, 95% CI 1.041-4.957), aPG IgG (OR 2.897, 95% CI 1.311-6.400), aPA IgG (OR 3.026, 95% CI 1.101-5.848), and aPS/PT IgM (OR 2.537, 95% CI 1.101-5.848). Here, CD40LG is linked to stroke disorder.