Thrombocytopenia was significantly associated with aCL IgG/M (OR 2.990, 95% CI 1.544-4.251), aβ2GpI IgG/M (OR 2.085, 95% CI 1.022-4.251), LA (OR 3.915, 95% CI 1.491-10.278), aPI IgG (OR 2.555, 95% CI 1.332-4.901), aPS/PT IgG (OR 2.146, 95% CI 1.113-4.135), and aPS/PT IgM (OR 3.310, 95% CI 1.718-6.375). The gene discussed is CD40LG; the disease is Thrombocytopenia.