While levels of some complement and coagulation proteins (C2, FX, FXI, FV, MASP2 and SERPINA5) correlated with specific parameters of disease severity (Figure 6C), levels of the C7 and FII proteins positively correlated with total disease severity (including severity of sleep episodes, cataplexy, hallucinations, sleep paralysis and night sleep quality) in NT1 patients from both cohorts (Figure 6D). Here, C2 is linked to Cataplexy.