Here, five groups of mice were used: The first group was injected with U251 Luc cells alone, the second one was co-injected with tumor cells and Dual-RevCAR T cells, and the third, fourth and fifth groups were co-injected with tumor cells and Dual-RevCAR T cells either with one RevTM or with a combination of two RevTMs (RevTM EGFR-7B6 + GD2-IgG4-5B9) (Figure 8). The gene discussed is EGFR; the disease is neoplasm.