Then, several potential differentially activated pathways between tumor cells and other cells were selected, including IL17 signaling pathway (Supplementary Figure 13C), IFN-II signaling pathway (Supplementary Figure 13D), VEGF signaling pathway (Supplementary Figure 13E), PERIOSTIN signaling pathway (Supplementary Figure 13F), TWEAK signaling pathway (Supplementary Figure 13G), and PAR signaling pathway (Supplementary Figure 13H). The gene discussed is IL17A; the disease is neoplasm.