MAP1LC3B and Parkinson disease: A: Degradation of several sirtuin proteins in dopaminergic neuronal cells using different PD models.D: LUHMES cells were subjected to 1-methyl-4-phenylpyridinium, rotenone, and paraquat, which inhibit autophagy, and the autophagy-mediated degradation of sirtuin proteins in the presence or absence of the autophagosome-lysosome fusion inhibitor BafA1 was monitored.R: (1) Protein expression of sirtuin proteins and the MA mediator LC3B by Western blot and immunostaining.