Mutations in genes encoding proteins such as the ubiquitin-ligase parkin, PTEN-induced kinase 1 (PINK1), and the mitochondrial protein DJ-1 involved in the regulation of oxidative stress have been reported in autosomal recessive cases of PD (Moloudizargari et al., 2017; Bar-Yosef et al., 2019; Meng et al., 2019). The gene discussed is PRKN; the disease is Parkinson disease.