IFNG and aortic aneurysm: gene set enrichment analysis (GSEA) showed that compared to genes associated with unruptured aortic aneurysms, those associated with ruptured aortic aneurysms were significantly enriched in pathways related to E2F targets, interferon-gamma response, MYC target V2, mTORC1 signaling, glycolysis, and epithelial mesenchymal transition in peripheral blood erythrocytes (|NES| ≥ 1.75, P < 0.05, Figure 1G).