Importantly, we identified endothelial cell (CD31<sup>+</sup>Sele<sup>+</sup>Glut1<sup>+</sup>) and neutrophil (Ly6G<sup>+</sup>Lta4h<sup>+</sup>Sort1<sup>+</sup>) subsets that were closely associated with acute liver dysfunction during sepsis progression. This evidence concerns the gene SORT1 and Decreased liver function.