CD73 is expressed in a grouping of cell types, including leukocytes, myofibroblasts, endothelial cells and epithelial cells, and so on (9), particularly in tumor, immune and other related cells (10), such as macrophages, myofibroblasts, dendritic cells and NK cells (11), etc. CD73 is also expressed in neutrophils to a certain extent, which can propel liver regeneration and regulate inflammation (12). This evidence concerns the gene NT5E and neoplasm.