Serum concentration of IL-6, TNF-α, and CXCL10 were significantly higher in newly-weaned hamsters challenged by Omicron BA.2 or Delta virus than their age-matched mock controls (Figure 1(E)), indicating that systemic inflammatory responses were elicited by virus infection in newly-weaned hamster despite lower virus replication in respiratory tissues. Here, CXCL10 is linked to viral infectious disease.