Previous studies from our laboratory showed that SGO1 is overexpressed in breast cancers (including TNBC) and that it correlates with overexpression of the E2F3 transcription factor, and with poor prognostic factors, including centrosome amplification, chromosome instability, and the epithelial-to-mesenchymal transition (EMT) [23–25]. Here, E2F3 is linked to breast cancer.