STING1 and contact dermatitis: More strikingly, Western blot also revealed that pre-administration of DMXAA significantly up-regulated the decreased expression of STING in the spinal dorsal horn of mice following intrathecal morphine injection (F (2, 15) = 26.76, P < 0.0001, one-way ANOVA, Fig. 5C and D), dry skin (F (2, 15) = 122.6, P < 0.0001, one-way ANOVA, Fig. 5E and F) and contact dermatitis (F (2, 15) = 177.7, P < 0.0001, one-way ANOVA, Fig. 5G and H).