CD4 and Sezary syndrome: Furthermore, the presence of an abnormal CD3− CD4+ CD7− or CD3+ CD4+ CD7− T-cell population is not pathognomonic of lymphocytic HES as it can be found in epidermotropic T-cell lymphoma (Sézary syndrome, where the lymphocytic infiltrate is epidermal, whereas it is usually dermal in lymphocytic HES) or angioimmunoblastic lymphoma.