For example, among the strongest associations with the lead SNPs at the following loci include: CLEC16A, CD28, MICA, and ELMO1 with eosinophil counts; AHI1 with monocyte and neutrophil counts, asthma, and hay fever (also shared by CD28); and MICA with type 1 diabetes. This evidence concerns the gene CD28 and seasonal allergic rhinitis.