BMI, waist and hip circumferences, systolic and diastolic BP, ALT, TC, TG, LDL-C, fasting and 2-h serum glucose in subjects with obesity were all significantly higher than those in healthy controls (all p ≤ 0.001), HDL-C in subjects with obesity was significantly lower than that in healthy controls (p < 0.001) (Table 2). Here, GPT is linked to obesity due to melanocortin 4 receptor deficiency.