L-carnitine, short-chain acylcarnitines, and three carnitine-mediated enzymes: carnitine palmitoyltransferase 1 A (CPT1A), carnitine palmitoyltransferase 2 (CPT2), and carnitine acetyltransferase (CRAT) were all up-regulated in breast cancer tissues. The gene discussed is CRAT; the disease is breast cancer.