The fact that ACBPKD less-responsive cell lines exhibited lower expression levels of FAO-related genes such as Acadm (Medium-chain Acyl-coenzyme A Dehydrogenase) and Cpt1-A (Carnitine palmitoyltransferase I) (supplementary Fig S2D) suggests that ACBP mechanism of action is conserved across cancer types and is likely dependent on the metabolic state of the cancer cell. The gene discussed is DBI; the disease is cancer.