STING1 and carcinoma: Membranous/cytoplasmic immunohistochemical expression of STING, considered as an H-score > 5 (spanning from 5 to 290), was found in 53 of 146 samples (36%), including 9 of the 55 low-grade (G1–G2) tumors (16%), and 43 of the 90 high grade (G3–G4) carcinomas (48%) (Fig. 1), and one pancreatic metastasis, which represented the only available specimen from the corresponding case (patient 37).