SOD1 and amyotrophic lateral sclerosis: To determine whether altered SOD1 metabolism could play a role in non‐SOD1 ALS, we compared the half‐life of CSF SOD1 protein in sALS and C9ORF72 hexanucleotide repeat expansion carriers (C9HRE) to controls and found no differences suggesting that SOD1 turnover is not altered in non‐SOD1 ALS.