In patients with CRP levels 1–3 mg/L within the first 24 h of stroke, no significant increased risk of ischemic heart disease (HR 1.05, 95%CI 0.99–1.11) or Takotsubo cardiomyopathy (HR 0.95, 95%CI 0.53–1.71) was found when compared to those with CRP levels < 1 mg/L. Here, CRP is linked to Tako-tsubo cardiomyopathy.