Patients with CRP levels of 1–3 mg/L and > 3 mg/L had higher risk of the composite outcome (HR 1.10, 95%CI 1.05–1.52; HR 1.51, 95%CI 1.45–1.58), death (HR 1.43, 95%CI 1.24–1.64; HR 3.50, 95%CI 3.01–3.96), HF (HR 1.08, 95%CI 1.01–1.16; HR 1.51, 95%CI 1.41–1.61), AF (HR 1.10, 95% CI:1.02–1.18; HR 1.42, 95%CI 1.33–1.52) and ventricular arrhythmias (HR 1.25, 95%CI 1.02–1.52; HR 1.67, 95% CI 1.38–2.01) compared to those with CRP < 1 mg/L. This evidence concerns the gene CRP and atrial fibrillation.