However, analyzing the risk for secondary outcomes, patients with CRP levels 1–3 mg/L showed no significative increased risk of ischemic heart disease (HR 1.06, 95%CI 0.91–1.24), HF (HR 1.15, 95%CI 0.97–1.36), AF (HR:1.12, 95%CI:0.96–1.32), ventricular arrhythmias (HR 1.08, 95%CI 0.77–1.52) and Takotsubo cardiomyopathy (HR 1.16, 95% CI 0.39–3.45) compared to those with CRP levels < 1 mg/L. This evidence concerns the gene CRP and Tako-tsubo cardiomyopathy.