Furthermore, in the glycolytic pathway, sugar phosphorylation appears to control the virulence in mice (Wijnants et al. 2020), whereas a regulated depletion of fructose-1,6-bisphosphatase, a key enzyme also involved in gluconeogenesis, hampers the growth and capacity of infection in another mouse model (Rodeki et al. 2006). The gene discussed is FBP1; the disease is infection.