CDK4 and hepatocellular carcinoma: We determined apoptosis related proteins (including Bad, bcl2, Bax and cleaved Caspase3) and cell cycle-related proteins (including p21, Cyclin D1, CDK4, Cyclin E1, and CDK2) levels in HCC cells, and found that SATB2-AS1 promoted Bad, Bax, cleaved Caspase3, and p21 levels in HCC cells, but reduced bcl2, Cyclin D1, CDK4, Cyclin E1, CDK2 expressions.