RGS17 and hepatocellular carcinoma: Recently, micro-RNAs (miR), a group of evolutionarily conserved small regulatory RNAs that participate in the regulation of diverse fundamental biological processes [61], are found to directly target some RGS mRNAs and affect their levels, such as RGS17 that is proven to be the direct target of miR-203 [62], RGS12 that is targeted by miR-204-5p in stress-induced pathology [63], RGS4 that is regulated by miR-107 in hepatocellular carcinoma [64], and RGS3 that is mediated by miR-133a in gastric cancer [65].