RGS6 and familial pancreatic carcinoma: In addition, despite the role of tumor suppressor in breast cancer [105], bladder cancer [104] and lung cancer [106], RGS6 is indicated to be a molecule that potentiates carcinogenesis, and particularly, dysregulation of RGS6 has been demonstrated to be positively associated with several cancers, including ovarian cancer [134] and pancreatic cancer [107].