In the pathological data collected in this study, in male patients (p = 0.002), patients with EGFR mutations (p < 0.001), Single station lymph node metastasis (p = 0.017) and patients with a tumour diameter ≤ 3 cm (p < 0.001), SKN2 was prone to occur. The gene discussed is EGFR; the disease is neoplasm.