Herster et al. reported that RNA and antimicrobial peptide LL37 are massively complexed in neutrophil extracellular trap (NETs) in skin of psoriasis, triggering the release of TLR8/TLR13-mediated cytokines and NETs in neutrophils in vitro and in vivo, which further promotes inflammation [29]. This evidence concerns the gene TLR8 and psoriasis.