In support of local pleiotropy, we observed 20 local \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$r_g$$\end{document}rg s between AD and PD in genomic regions containing disease-implicated genes, such as SNCA (LD block 681, chr4:90,236,972-91,309,863) and CLU (LD block 1273, chr8:27,406,512-28,344,176). This evidence concerns the gene CLU and Alzheimer disease.