We also noted a positive correlation between AD and PD in LD block 2128 (chr16:29,043,178-31,384,210), which contains the AD-associated KAT8 locus26 and the PD-associated SETD1A locus3 (of note, rare loss-of-function variants in SETD1A are associated with schizophrenia40). This evidence concerns the gene KAT8 and Alzheimer disease.