Notch regulates in MCC precursors the expression of MULTICILIN/MCIDAS (MCI), a transcriptional coactivator protein, which establishes a core MCC transcriptome of about 800 genes with help from key downstream transcription factors, such as FOXJ1 and RFX2 (Quigley & Kintner, 2017). This evidence concerns the gene MCIDAS and Merkel cell skin cancer.