Among the cytokines constitutively secreted by leukemic MPP3, Gal3 is highly expressed in various cancers and is a negative prognostic factor for acute myeloid leukemia patients (Cheng et al., 2013; Liu and Rabinovich, 2005; Yamamoto-Sugitani et al., 2011). The gene discussed is LGALS3; the disease is acute myeloid leukemia.