IFNG and neoplasm: In contrast to exogenous GC use, stress-induced durable augmentation in the endogenous GC tonus inhibits IFN-γ expression in tumor-infiltrating T cells and decreases plasma concentration of cytokines and chemokines, such as IFN-β, IL-15, IL-23A, CXCL10, CXCL1 and CXCL9, and these changes were also long-lasting.