L > Phe (F) at position 35 (Figure 3A), E > D at position 55 (Figure 3B), Met (M) > V at position 205 (Figure 3C), and Asp-Glu-Ala-Val-Lys-Ile (D-E-A-V-K-I) > Gly-Gly-Pro-Met-Arg-Thr (G-G-P-M-R-T) at positions 84-85-86-87-96-170 of HLA-DPβ1 in ICI-T1DM (Figure 3D). This evidence concerns the gene HLA-DPB1 and type 1 diabetes mellitus.