Interestingly, we detected BCR-ABL fusion in TL_2, TL_6, and TL_8, which suggests that these samples could have a CML origin with primary blast crisis, which is the case with TL_2, or they could belong to the recently discovered rare category of AML, which are BCR-ABL positive (Neuendorff et al., 2016). This evidence concerns the gene ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive.