Notably, one (sample ULM7.6) out of these four MED12 mutation-positive fibroid also have missense mutation (M1L) in exon 1 of FH. In the case of this patient, it sets the foundation for further investigation to analyse the protein expression patterns in FH mutation-positive and mutation-negative uterine fibroids and relate to MED12. The outcome of this investigation will lead to the identification of protein expression patterns associated with MED12 and FH as biomarkers for diagnosing uterine fibroids. The gene discussed is FH; the disease is uterine corpus leiomyoma.