For example, MX2 of naive B cells and CD163 and IFIT1 of CD14+CD16+ monocytes in peripheral blood of dengue patients were significantly upregulated before onset of dengue fever, indicating that these genes with significantly altered expression levels have the potential to be biomarkers for predicting dengue disease (Zanini et al., 2018). This evidence concerns the gene IFIT1 and dengue disease.