Late-life SBP correlated negatively with frontal WM PDGFRB in dementia cases (r = −0.1821, P = 0.0413; Supplementary Fig. 4F) but not controls (ns; Supplementary Fig. 4E) and not in the parietal WM in either group (both ns; Supplementary Fig. 4G–H). The gene discussed is PDGFRB; the disease is dementia.