PLP1 and early-onset autosomal dominant Alzheimer disease: In all dementia cases (i.e. combining Alzheimer’s disease, mixed and vascular dementia) but not controls, MAG:PLP1 in the FC correlated positively with DBP (Pearson’s r = 0.1985, P = 0.0259, n = 126) and PC (r = 0.1971, P = 0.0282, n = 124) but not with SBP (Fig. 2).