Previous studies have evaluated the presence of IgG subclasses’ anti-RBD, and reported that the most prevalent subclasses were IgG2 (60.47%) and IgG1 (53.49%), followed by IgG3 (44.19%) and IgG4 (2.33%) during the first 30 days of infection [37], whereas specifically against N protein, a seroprevalence of 70% to IgG1, 67% to IgG3, 52% to IgG2, and 45% to IgG4 during the first 7–62 days post-infection has been reported [38]. The gene discussed is IGHG3; the disease is infection.